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The Mediterranean diet: a potential shield against cognitive decline

A recent French study confirms it: the Mediterranean diet helps to prevent cognitive decline in older people

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In most industrialised countries, longevity has continued to rise to this day. Life expectancy has risen steadily and people are getting older. We are therefore faced with a health phenomenon that is becoming numerically ever more significant: cognitive decline.

If we consider that the average age of the population in Italy is 47, among the highest in Europe, the negative side of this phenomenon emerges ever more significantly, also in light of the study carried out in the UK, which suggests that the problem worsened after the COVID-19 pandemic.

The UK's PROTECT study has provided discouraging data on cognitive decline in older adults during and after the COVID-19 pandemic. The study monitored the cognitive health of individuals over the age of 50, tracking their cognitive functions over several years, including the periods before and during the pandemic.

The results of the study show a significant acceleration in cognitive decline during the first year of the pandemic, even among those who did not contract the virus. Factors such as increased loneliness, reduced physical activity and higher alcohol consumption during lockdowns were considered among the causes of the deterioration in cognitive functions, even in relatively young people.

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But the most worrying aspect is that the prolonged impact of these factors in the second year of the pandemic suggests long-term consequences for brain health.( ean.org)​​ (ORE Exeter)​​ (News)​.

So this phenomenon does not stem only from longer life expectancy, but also from extraordinary external factors, and it is also closely linked to our diet. A glimmer of hope comes from recent studies, including the renowned French Three-City Cohort Study, which suggests that the Mediterranean diet could be one of the keys to ‘shielding’ the mind against the erosion of time.

This study included around 800 older participants with an average age of 75 at baseline, focusing on the assessment of cognitive function over a 12-year period. The study used an innovative methodological approach that quantifies adherence to the Mediterranean diet through specific biomarkers in serum.

These biomarkers reflect the intake of food groups typical of the Mediterranean diet, such as unsaturated fatty acids and polyphenol metabolites derived from the gut microbiota, which are crucial for assessing the bioavailability of these compounds​ (Med Xpress)​​ (Technology Networks)​.

What were the results?

The results of the study revealed a 10% reduction in the risk of cognitive decline among those who adhered most closely to the diet, based on these biomarkers​ (Universitat de Barcelona)​. Although the numerical effect may appear modest, this reduction is clinically significant, especially considering that there is currently no cure for cognitive decline conditions.

Moreover, the use of dietary pattern indices based on the assessment of biomarkers represents an advance in nutritional research, offering more accurate and objective methods that take into account crucial factors such as bioavailability​ (Med Xpress)​.

While it is by now well established that diet is fundamental to people’s health, these results strengthen the belief that dietary choices, particularly those in line with the Mediterranean diet, play a significant role not only in well-known conditions such as cardiovascular disease, but also in maintaining cognitive health, which is sorely tested as we age.

The rise in the average age in Europe, and above all in Italy, demands ever greater attention to people’s mental clarity and intellectual abilities. Demographics and the needs of pension institutions around the world are forcing states to extend working lives ever further, so that people are ‘forced’ to work until an age that only a few decades ago was considered advanced.

It is therefore important that older people maintain normal cognitive abilities as far as possible, both for their own sake and for the preservation of the social fabric. The studies in question suggest that diet may be a vital component of strategies aimed at reducing the risk of cognitive decline among older people (Technology Networks).

This is in fact in line with broader research indicating that the Mediterranean diet not only supports the ability to stay ‘sharp’, but also helps to reduce the risk of chronic diseases.

Studies conducted by universities such as the Universitat de Barcelona show that a diet rich in fruit, vegetables, wholegrain cereals, pulses, nuts and olive oil, with limited consumption of red meat and moderate use of wine, can have beneficial effects in preventing diseases such as diabetes, hypertension and cardiovascular disease. These benefits derive from the essential nutrients and antioxidants found in these foods, which fight inflammation and promote the health of the blood vessels, essential for maintaining good cognitive function and general physical wellbeing.

other sources and further reading:

For more details on the studies on cognitive decline after COVID-19, you can explore the study published in ‘The Lancet Healthy Longevity’ and further information available on the PROTECT study web page on the University of Exeter website or directly through their study portal​ (ean.org)​​ (ORE Exeter)​​ (News)​.

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